Vitex studies. Explore Our Case Studies! Skip to content.

Vitex studies If taken regularly for several months, it helps to restore hormonal balance and alleviate PMS symptoms. In many inflammatory disorders there is excess activation of phagocytes and Extensive clinical studies as well as over two thousand years of use have proven the effectiveness of this remedy. plants. Setting: General medicine community clinics. 20%) of M. Search strategy. Chasteberry (Vitex agnus-castus) is the fruit (berries) from the chaste tree. str. In 19th century, the developmental studies could complete the anatomical perusals. documented in ayurveda is to provide mental peace. It is a well known fact that LH secretion from the anterior pituitary of mammals is controlled by many neurotransmiters such as dopamine. MALLIKARJUNA RAO Department of pharmaceutical sciences, Andhra university, Visakhapatnam – 530 003, Andhra Received: 20 December, 1996 Accepted: 16 May 1997 ABSTRACT: Vitex leucoxylon is known to possess anti inflammatory activity. Mortality was recorded 24, 48 and 72 h post-exposure to “Vitex is a classic female herb often recommended by herbalists to relieve unpleasant symptoms of PMS. The pooled treatment effects should be viewed as A comparative study investigating the pharmaceutical Bromocriptine and the herbal medicine Vitex agnus-castus found no side effects associated Vitex agnus-ca stus compared to 12. , and Vitex agnus-castus can impact on menstrual and ovulatory dysfunctions, obesity, insulin resistance, lipid-metabolism dysfunction, and This study aimed to assess the efficacy and safety of Lagundi (Vitex negundo) tablets and syrup in patients with mild COVID-19 without comorbidities. In this study, Vitex agnus-castus (Vitex), which has antioxidant effects and high levels of phytoestrogen, was investigated with regard to the hypothalamic-pituitary-gonadal axis and antioxidant indices in natural aging and in a d-galactose induced aging model in female mice. Introduction: Herbal medicine containing Vitex agnus-castus (VAC) extract is widely used by women with premenstrual syndrome (PMS) in Europe, however, in Japan, clinical evidence remains to be determined. (chaste tree; chasteberry) is a popular herbal treatment, predominantly used for a range of female reproductive conditions in Anglo-American and European practice. This study was carried out to investigate its cough-relieving potential. Methods: This review article was carried out by searching studies in PubMed, Medline, Web of The selection of explants in Vitex in vitro studies tends to be from young and actively growing shoots or branches, with shoot tips and nodal explants with dormant axillary buds being the first choice (Table 2) due to the presence of a predetermined meristem which allows for true-to-type clonal propagation. Inspired by the medicinal properties of this plant, the current study aimed to investigate antiproliferative potential and the primary molecular mechanisms of the apoptotic The studies in which VAC was assessed in association with other medication were excluded. Among 250 species in the Vitex genus, V. Then, the aim of this study is to summarize traditional uses, phytochemistry and pharmacological activities of 2 local species of Vitex. (3) Methods: The oils were subjected to GC-MS and mosquito behavioral analysis. A study reported that ISHS Proceedings of the 2015 Annual Meeting of the International Plant Propagators' Society Seed germination studies of Vitex agnus-castus© Vitex would benefit from additional breeding in order to develop new characteristics such as a Antimicrobial studies indicated that the ethanolic leaf, root and stem extracts of Vitex chrysocarpa inhibited the growth of the pathogens but at varied levels and the inhibition was extracts Studies have also found that an extract from Vitex seeds can repel mosquitoes, ticks, flies, and fleas for up to six hours. Modern clinical use for treating cold headaches, diarrhea dysentery, irregular menstruation Introduction Vitex agnus-castus, also called Vitex, is a plant with many medicinal properties. 9 % of 20 participants administered Vitex (20 – Objectives: To compare the efficacy and tolerability of agnus castus fruit ( Vitex agnus castus L extract Ze 440) with placebo for women with the premenstrual syndrome. Most studies were performed with the Vitex quinata (Lour. This study aimed to evaluate the safety of this herb through acute and sub-chronic toxicity evaluation of aqueous ethanol Vitex negundo Linn. Vitex agnus-castus is a herb, also known as Chaste Tree, Chasteberry and Monk's Pepper. KEYWORDS: Vitex negundo, Phytoconstituents, Medicinal use, Pharmacological Vitex negundo L. Among these, there . Participants took 3 different doses of VAC or placebo for 3 menstrual cycles. [101] Zheng CJ, Tang WZ, Huang BK, Han T, Zhang QY, Zhang H, et al. Average percent germination of Vitex agnus-castus seeds when soaked in 5000 ppm gibberellic acid (GA3) followed by scarification for 0 minutes (control), 15 minutes (A15M GA), 30 minutes (A30M GA), and 60 minutes (A60M GA). It is a prevalent Asian aromatic shrub, and it is distributed from tropical to temperate regions [7]. However, larger studies of high quality are needed to corroborate it. Objectives In this study, we aim at deciphering the phenolic content of Vitex agnus-castus L. R. negundo is a reputed drug in Ayurveda 1 and is beneficial in inflammatory disorders. A er going through the full-text articles a total of 18 . In this experiment, we have studi Numerous studies have suggested that chasteberry may help reduce symptoms of PMS, including breast tenderness, headache and irritable mood. Design: Randomised, double blind, placebo National Center for Biotechnology Information A comparative study investigating the pharmaceutical Bromocriptine and the herbal medicine Vitex agnus-castus found no side effects associated Vitex agnus-ca stus compared to 12. The results of this study show that the species of this Objectives: To compare the efficacy and tolerability of agnus castus fruit (Vitex agnus castus L extract Ze 440) with placebo for women with the premenstrual syndrome. The maximum mortality (97. The purpose of this study was to evaluate the probable effects of Vitex agnus castus (Vac. | A total of 143 endophytic fungal isolates were recovered from 1350 bark, twig and leaf segments of Vitex negundo L Some studies have suggested that Vitex may help to ease these symptoms by supporting hormonal balance during this transitional period. and V. Traditionally, V. 5% of participants taking Bromocriptine reporting nausea and vomiting . However, because herbal medicines are The present study was carried out to characterize the bioactive constituents present in different leaf extracts of Vitex altissima L. , commonly known as chaste tree, is a small deciduous tree whose fruits have been used for over 2500 years in ancient Egypt, Greece, Iran and Rome for various gynecological RESULTS In pregnancy, there is poor evidence based on theoretical and expert opinion and in vitro studies that chastetree may have estrogenic and progesteronic activity, uterine stimulant activity, emmenagogue activity and prevent miscarriages. KRISHNA RAO, RANJIT JENA and P. rotundifolia to provide additional insights into their . MATERIALS AND Tw o studies compared Vitex extracts with f luoxetine in PMDD. Materials and methods This systematic Vitex negundo L is a medicinal plant with many notable therapeutic effects. Results: This review includes 25 studies (17 randomized control trials plus eight nonrandomized trials). l. Normally about 5% of the inhaled oxygen is converted to harmful reactive oxygen species like O 2 −, H 2 O 2, •OH 2. Menu. g. Lagundi (Vitex negundo), a medicinal herbal cough remedy widely used in the Philippines, was considered a potential adjunctive treatment for COVID-19. leaf extracts were screened for their phytochemical composition and antioxidant activity. negundo (Vn) on sulphur dioxide (SO(2))-induced cough Aging is associated with the loss of endocrine function. Discover Our Success Stories in Test Equipment! Skip to content. bicolor, V. It works by stimulating and normalizing the pituitary gland, which regulates the balance of estrogen and progesterone in The review includes 161 references on the genus Vitex, and comprises ethnopharmacology, morphology and microscopy, phytoconstituents, pharmacological reports, clinical studies, and toxicology of Article: Phytochemical studies on the leaves of Vitex negundo, L. 2 feet). Request PDF | Diversity studies on the endophytic fungi of Vitex negundo L. Using Soxhlet extractor five successive extracts from dried and powdered leaves were also taken. The plant is called a "chaste tree" or "nirgundi" in common, and it belongs to the Verbenaceae family and Vitex Background: Preparations of Vitex agnus castus L. The “right” dosage for you depends on many factors, such as sex A systematic review done in 2017 analyzed the use of Vitex versus placebo or active treatment of PMS or PMDD in eight different studies. In one review conducted by the Royal Melbourne Institute of The first trial of two essential oils (derived separately from leaf and fruit) of Vitex agnus castus for menopausal balance was conducted in the summer of 2000 by the author. Figure 3. N. (Verbenaceae) is a hardy plant, flourishing mainly in the Indian subcontinent. 6 to 26. , agnoside, aucubin), diterpines (e. ) F. This study aimed to evaluate the therapeutic efficacy of Vitex negundo seed in a letrozole-induced PCOS rat model. In one open study, 118 people with acne were treated with a fruit extract (20 drops twice daily for 4–6 weeks, then 15 drops twice daily for 1–2 years) and Abstract Objective: Polycystic ovary syndrome (PCOS) is an endocrine system disruption that affects 6-10% of women. This review supports all updated information on its phytochemical and pharmacological activities, traditional uses and scientific V. KEY WORDS: Vitex negundo, phytochemicals ,secondary metabolites, Thin layer chromatography . However, the treatment effect of VAC on CM remains unclear. is one of the important plant from traditional system of medicine found all over the world. Thirteen of 14 studies 301 Figure 2. SAFETY AND EFFICACY OF CHASTETREE (Vitex Agnus-Castus) DURING PREGNANCY AND LACTATION Jean-Jacques Dugoua1,2,3, Dugald Seely3,4, In pregnancy, there is poor evidence based on theoretical and expert opinion and in vitro studies that chastetree may have estrogenic and progesteronic activity, uterine stimulant activity, emmenagogue Research studies use different vitex dosages—generally between 4 and 40 milligrams (mg)—when investigating the herb's effect on various conditions. invitro studies ha ve been identi ed. The bark is 5. Vitex Talks | Upgrade your network infrastructure with the new 800G QSFP-DD optical transceiver Continue reading > In this 5-minute Vitex Talks white board video, we’re shining a light on Purpose: This study aimed to perform the comparative phytochemical study, chromatographic profiling, and Antiurolithiatic activity of Vitex negundo linn root extracts. Inspired by the medicinal properties of this plant, the current study aimed to investigate antiproliferative potential and the primary molecular mechanisms of the apoptotic induction Vitex negundo L. Few studies have shown that Vitex agnus-castus improves sexual dysfunction in postmenopausal women; the present study was conducted to evaluate the effect of V. What Are the Side Effects of Vitex? Vitex can cause minor side effects like stomach upset or nausea in some patients. In three of the studies Vitex was compared to fluoxetine (an anti-depressant) Vitex agnus castus is a hypothalamic–pituitary–ovarian (HPO) regulator, and because HPO imbalance is associated with PCOS, it is likely to be of benefit in managing the condition. The yield of phytochemicals is in the order of ethanol extract > methanol extract > benzene extract > chloroform extract > hexane extract > ethyl acetate extract > petroleum extract. The effects of these extracts were examined on the germination percentage and several In the present study, Vitex negundo L. leaf and fruit extracts prepared with different methods and relate it to their antioxidant activity. Methods: Using maceration extraction, Successive reflux condensation extraction processes were used to prepare petroleum ether, methanol, aqueous, and alcoholic extracts. There was evidence for an equivalent effect of two herbal medicines and the pharmaceutical agents bromocriptine (and Vitex agnus-castus) and clomiphene citrate (and Cimicifuga This research aimed to determine the effectiveness of Vitex agnus-castus extracts in alleviating menopausal symptoms in comparison with that of placebo. negundo study also showed many Phytochemicals Hexanoic acid, ethyl ester, 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-, Hexadecanoic acid, ethyl ester, Caryophyllene, A chemical analysis report of various studies identified that Vitex exhibited a wide range of phytoconstituents, such as iridoid, diterpenoid, ecdysteroid, and flavonoid and phenolic compounds Elevate Network Efficiency with Vitex: Discover How We Eliminated Downtime and Boosted Performance in Our Case Studies! Skip to content. antibacterial studies o f Vitex negundo Linn. Our study was undertaken to ascertain the analgesic properties of Vitex negundo seeds, and to characterize the active constituents. Copper Oxide/Carbon nanocomposites (CuO/C NC) have been synthesized via a green strategy by using the aqueous leaf decoction of Vitex negundo Linn for its application in the degradation of Methylene Blue (MB), Coomassie Brilliant Blue (CBB), and Congo Red (CR) dyes. The daily dose was one capsule (20 mg) Vitex agnus castus preparatio Background Polycystic ovary syndrome (PCOS) is a complex endocrine disorder in women that necessitates effective and safe treatment alternatives. Various experimental studies have been conducted on this plant by professionals all over the world. trifolia s. Also, due to the Vitex negundo is a woody plant mainly found in Indian subcontinent and its neighbouring countries. (V. VAC was effective in relieving breast pain The current study investigates the nematicidal potential of green-synthesized silver oxide nanoparticles derived from Vitex negundo against second-stage juvenile (J2) and eggs of M. Investigations of the bronchial relaxing constituents. Ως βιομηχανία χρωμάτων μας χαρακτηρίζει η ποιότητα των προϊόντων & η καινοτομία στην τεχνολογία! Vitex negundo is an erect, branched, deciduous shrub or small tree, 2–5 m tall, with a slightly rough, pale reddish-brown bark that peels off in papery flakes. It is mostly marketed for menstrual disorders, including symptoms of premenstrual syndrome and/or menopause, as well as for acne. trifolia is one of the very well-known species and is commonly being used in Vitex studies. quinata led to the isolation of five compounds, namely, daucosterol, 3,5-O-dicaffeoyl quinic acid, 20-hydroxyecdysone 20,22-monoacetonide, β-sitosterol, and vitexin, but with no biological data In this study we investigated the effects of storage and hydration-dehydration regimes on Vitex doniana seed viability, germination speed and seedling growth and vigour. An identified reference germplasm is needed to facilitate the stable sourcing of medicinal plants with correct genotype(s). This study was conducted to investigate Vitagnus effect on the expression of kisspeptin gene in a rat model of PCOS. var. 201-296-0145. The results of the current study conclude that the nutraceutical composition of Vitex agnus-castus extract, vitamin B6, and magnesium is effective in reducing the severity of PMS Vitex negundo: Medicinal Values, Biological Activities, Toxicity Studies, Phytopharmacological Actions The genus Vitex is also known as a chaste tree, in which it is a large shrub native to the tropical and subtropical regions of the world. Our Test Equipment Case Studies. This systematic study examined the evidence of the effectiveness and safety of Vitex on menstrual bleeding (primary outcome) and its side effects (secondary outcomes). The structure of two compounds extracted from the leaves of Vitex negundo L. and Vitex trifolia L. bicolor through next-generation sequencing and compared this to earlier established chloroplast genomes of V. documented in ayurveda One such efficient plant is chosen for the extraction, purification, and isolation of biologically active compound, artemetin in our study, it is Vitex negundo. Most studies on chaste berry for infertility or PCOS have used a blend of herbs, making it difficult to determine the role of a solitary component. Results Findings of the present study demonstrated that administration of hydro-ethanolic extract of Vitex is great for supporting your body in balancing hormones naturally. 42. Two compounds were purified and a residual film bioassay was used to evaluate the toxicity to adult T. , apigenin, castican, orientin, isovitexin). Methods In this study, phenolic compounds and In this study, the characterization of hydroxycinnamic acid, saponins, allicins, flavonoids, and terpenoids from Vitex doniana was carried out using gas The herb vitex can help the body establish a proper balance between estrogen and progesterone by encouraging the production of progesterone. Panicles are terminal, slightly hairy, many-flowered, Introduction: Vitex agnus-castus, also called vitex is aboriginal to the Mediterranean region, with long leaves, tender stem, flowers and ripening seeds. This was a 2-stage multicenter parallel Ανακαλύψτε τα ιδανικά χρώματα. J Biol Active Prod . rotundifolia are part of a species complex that has recorded medicinal use in the Philippines. have a variety of pharmacological activities, such as anti-tumor, analgesic, antipyretic, anti-inflammatory, antioxidant, antibacterial, and estrogen-like activity. Here we review the evidence for this application of Vitex based on evidence from pharmacological studies and clinical research. using UV-VIS, FTIR and GC-MS. It Background: Vitex negundo L. Herbs such as Cinnamomum verum, Trigonella foenum-graecum L. Introduction There’s no official dosage recommendation for vitex, though many studies use 20 to 40 milligrams as the daily amount. Phytotherapy is a practice of treating with plants or plant components. It is believed that administration of this plant extract has Request PDF | Adsorption studies of Methylene Blue, Coomassie Brilliant Blue, and Congo Red dyes onto CuO/C nanocomposites synthesized via Vitex negundo Linn leaf extract | Copper Oxide/Carbon Vitex species possesses numerous biological activities proved by many experimental studies. The participants were randomly divided Vitex agnus-castus L. Yet, there is no consensus on its treatment. Fourteen of these could be included in the quantitative analysis. Topic: Plants used in traditional medicine represent a priceless tank of new bioactive molecules. The main findings of this review indicate that 2 herbal extracts, fenugreek seed extracts and ashwagandha root and root/leaf extracts, have positive effects on testosterone concentrations in men. The antitussive effect of the butanolic extract of V. Methods: This study was a randomized controlled double-blind clinical trial with a study group of 52 women referred to a clinic in Kermanshah in 2017. Inspired by the medicinal properties of this plant, the current study aimed to investigate antiproliferative potential and the primary molecular mechanisms of the apoptotic PDF | Vitex negundo L. We aimed to evaluate phytochemical and agro-morphological properties of four pre-selected, genetically stable, and native Vitex trifolia s. Vitex negundo L. The aim of our work was to evaluate the efficacy of VAC in PMS. ) on the male reproductive physiology. Cuspor D, et al. accessions from the Philippines to provide baseline information and present promising and Some plants as natural remedies may have beneficial effects on improving different aspects of PCOS; but further studies are needed to investigate their mechanisms and safety. Pharmaceutical Sciences, 2008; 70: 522-526. The chemical constituents of essential oil The efficacy of a Vitex agnus castus preparation (Strotan capsules) was investigated in a randomized double blind study vs. Methods: A multi-center, prospective, open-label, analgesic studies of essential oils of Vitex ne gundo Linn. Explore Our Case Studies! Skip to content. However, the dose-effect relationship for the treatment of PMS has not yet been established. The alarming and rapid increase in the antimicrobial drug resistance globally has led to the development of Vitex negundo L. Vitex negundo (L) is a tiny tree or shrub that grows to a height of 2 to 8 m (6. Methods: A double blind, placebo-controlled study of the effects of FertilityBlend for Women, a proprietary nutritional supplement containing chasteberry, green tea, L-arginine, vitamins (including folate) and minerals, on progesterone level, basal body temperature, menstrual cycle length, An Updated Snapshot of In Vitro and In Vivo Studies on Vitex agnus-castus. Vitex negundo seeds have been commonly used as folk medicine in southern China for the treatment of various pain disorders. We found 17 randomized controlled trials of Vitex agnus castus in the treatment of premenstrual syndrome. incognita. In premenstrual dysphoric disorder, In this current study, Vitex agnus‐castus seed ethanol extracts were analyzed for their phytochemical component content, anticholinergic and antioxidant activities, and antibacterial properties. Plant development studies Preclinical and clinical studies provide evidence that six herbal medicines may have beneficial effects for women with oligo/amenorrhea, hyperandrogenism and PCOS. Casticin, chrysoplenol D, luteolin, p-hydroxybenzoic acid, D-fructose and isoorientin were isolated and identified from 2 pharmacologically active Vitex negundo is an aromatic shrub distributed worldwide with several medicinal properties. Optical Transceivers. Its fruit has been used for more than 2500 years as phytotherapic agent. agnus-castus on the female sexual function in the reproductive age. In the present study Essential oils from fresh leaves, flowers and dried fruits of Vitex negundo were obtained by hydrodistillation. Williams is a 4–12 m tall evergreen tree found mainly in temperate and tropical Asia (Chen and Gilbert, 1994). This study attempted to investigate the efficacy and safety profiles of VAC extract in Japanese patients with PMS. Also, some evidence exists for another Revolutionize Testing with Vitex's Lightning-Fast CWDM Channel Analyzer. . Search 32 Mercer St, Hackensack, NJ 07601-5622. Every part of the plant is enriched with therapeutic value; hence the plant plays a In short, the advantages of this study compared to other studies include the use of Vitex plant extract orally, which can include the following: The preparation of nano-fiber Nano pads containing medicine allows the medicine to be provided to the patient continuously and with a uniform dose during the treatment period. • Antifungal: (1) New antifungal flavonoid glycoside from Vitex negundo: Study found a new isolated flavone glycoside and a known compound to have significant antifungal activity against Trichophyton mentagrophytes and Cryptococcus neoformans. A VACF extract has recently been shown to exhibit antitumor activities in different human cancer cell lines. Among the 80% ethanol extract and some fractions with different polarity, the acetoacetate Abstract. Health professionals should be aware that some studies indicate Vitex agnus-castus may bind estrogen [1] and dopamine Explore Our Case Studies! Unlock Massive Savings in Telecom: See How Vitex's Coded Optics Delivered Over 40% Cost Reduction. The third section presents some observation on the medicinal plant resources in the study Effects of Vitex agnus-castus extract on the secretory function of pituitary-gonadal axis and pregnancy rate in patients with premature ovarian aging (POA) [44]. (2) This research update details the result of the Vitex agnus-castus (VAC) is known for its dopaminergic activity and its possible actions on CM and latent hyperprolactinemia. PDF | On Jan 10, 2016, C Ilodibia and others published Proximate, Vitamin, Mineral and Anatomical Studies on Vitex chrysocarpa Planch ex Benth. Previous studies showed that vitex interacts with neurotransmitter and neural system, such as dopaminergic, serotonergic which are involved in modulation of anxiety (-). , limonene, sabinene, 1,8-cineole [eucalyptol]), iridoid glycosides (e. Additional research revealed that Vitex can not only kill lice but also prevent lice reproduction. No studies comparing the effectiveness for herbal medicines and the oral contraceptive pill in Purpose: To determine the impact of nutritional supplementation on female fertility. This plant is commonly used in the preparation of traditional drugs to treat numerous diseases. Ooi SL, Watts S, The results of the current study conclude that the nutraceutical composition of Vitex agnus-castus extract, vitamin B6, and magnesium is effective in reducing the severity of PMS symptoms and improving the quality of life of PMS subjects. negundo) is one of the important medicinal and anticancer enhancer herbs. (Verbenaceae) | Find, read and cite all the research Pharmacological studies have shown that Vitex rotundifolia L. This review aims to focus the medicinal values of Vitex negundo. In present study, we aimed to investigate the anti-inflammatory effects of V. However, to the best of our knowledge, there has been no study comparing the efficacy of the SRIs with Vitex ag Objectives In this study, we aim at deciphering the phenolic content of Vitex agnus-castus L. Vitex negundo Linn is an important medicinal plant belonging to the Verbenaceae family. , their repellent activity and toxicity against three strains of Tribolium castaneum (Herbst) were elucidated. Nat 2012; 4 (2): 239-49. In an open study Keywords: Vitex negundo, macroscopical studies, microscopical studies, identification and evaluation 1. 1. ex tra cts', Indian Journal of . agnus-castus extracts in the treatment of premenstrual syndrome, premenstrual dysphoric disorder, and latent Introduction:Vitex Leucoxylon Linn. In premenstrual Vitex agnus-castus L. This study aimed to investigate the clinical effects of three different doses of the From the 4 databases searched, there were 13 herbs identified in 32 studies, published between 2001 and 2019. a member of family Verbenaceae, is an erect aromatic shrub with 2–5 m height, distributed widely in Southwest Asia including; Philippine, India, China, and Pakistan (Falguni et al. The plant is known and antibacterial studies of Vitex negundo Linn. The study is focussed on the in vitro antioxidant, antimicrobial, anti-hemolytic and anti-proliferative activity of Vitex negundo leaf, extracted with four different solvents based on polarity. V. , known as the chaste tree, is a small deciduous tree which its fruits have been used for more than 2500 years in ancient Egypt, Greece, Iran, and Rome for a variety of In this study the therapeutic effect of Vitex agnus castus on women who had the PMS, in comparison with placebo, were investigated. (lagundi). Some studies have reported the effect of Vitex agnus-castus (Vitagnus) on the hypothalamic-pituitary-gonad axis (HPG). ) Rehder (Lamiaceae) is an important tree species for soil and water conservation, yet the reproductive ecology of this species remains to be elucidated. The nutraceutical therapy provided greater relief from PMS symptoms compared to standard therapy alone, and According to a multitude of studies, a wide spectrum of herbs can be used to improve various aspects of PCOS. The characterization techniques such as FTIR, XPS, UV–Visible spectroscopy, FE-SEM, and Vitex negundo L. agnus-castus, but often applied to Studies of the beneficial effects of Vitex Agnus Castus L. , vitexilactone, rotundifuran), and flavonoids (e. (VAC) have been shown to be effective to treat irregular menstrual cycles, cyclical mastalgia and symptoms of the premenstrual syndrome (PMS). (2) Aim: This study examines the interaction between the constituents of Vitex negundo essential oil and Anopheles gambiae Odorant Binding Proteins (OBP) as well as the compositional variation, repellent efficacy, and toxicity profile. extrac ts', Indian Journal of Pharmaceutical Vitex agnus-castus is a small tree or shrub, belonging to the family Verbenaceae. We found no published studies on Vitex negundo on patients with COVID-19 but there is one completed local clinical trial whose full results are not yet available. (Verbenaceae) is a hardy plant widely distributed in the Indian subcontinent and used for treatment of a wide spectrum of health disorders in traditional and folk medicine, some of which have been experimentally validated. Keywords: National Institutes of Health; National Center fo Vitex species are well known in pharmacology to have medicinal values, such as anti-inflammatory, antibacterial, antifungal, antimicrobial, antioxidant, and anticancer properties. In this randomized, placebo-controlled, double For premenstrual syndrome, seven of eight trials found Vitex extracts to be superior to placebo (5 of 6 studies), pyridoxine (1), and magnesium oxide (1). Vitex negundo Linn is a n Indian plant which having wide variety of pharmacological actions. Botanical studies, cultivation, and Vitex agnus-castus L. A total of 161 compounds from different Vitex species are Abstract BACKGROUND: Sexual dysfunction in women is a common disorder. Vitex / ˈ v aɪ t ɛ k s / [3] is a genus of flowering plants in the sage family Lamiaceae. Results: Preclinical studies confirmed the binding of VAC The studies on Vitex negundo leaves were showed good potential to utilize this plant for commercial purposes. A previous study on V. f. Vitex* / chemistry Substances Menstruation-Inducing Agents Vitex species possesses numerous biological activities proved by many experimental studies. Design: Randomised, double blind, placebo controlled, parallel group comparison over three menstrual cycles. I. Trigonella foenum-graecum L. The leaves are opposite, digitately three to five foliolate (Figure 57. For premenstrual syndrome, seven of eight trials found Vitex extracts to be superior to placebo (5 of 6 studies), pyridoxine (1), and magnesium oxide (1). (2) Ethanol extract of fruit seeds showed significant activity against Fusarium solani and moderate Clinical trials have demonstrated that serotonin reuptake inhibitors (SRIs) and the extract of Vitex agnus castus are effective for the treatment of premenstrual dysphoric disorder (PMDD). V. While the beneficial effects of Vitex negundo have been widely described, evidence of this herb’s safety, such as acute and sub-chronic toxicity effects, remains scarce. Clinical studies verify its ability to relieve cramps, breast tenderness, and mood swings associated with the menstrual cycle, even when compared with conventional pharmaceuticals. The aim of this study was to overview premenstrual, postmenstrual and infertility disorder of Vitex agnus-castus. (family Verbenreae) is found commonly in India. It is a deciduous shrub native to European, Mediterranean, and Central Asian countries. 2019 Dec;47:102190. Alternative explant sources Thesis Title Study of α-Glucosidase and α-Amylase Inhibitory Activities of Thai Folk Anti-Diabetes Remedies and Phytochemical Study of Vitex glabrata Stem Bark and its Chemical Constituents Author Miss Pitchanan Thiantongin Major Program Vitex negundo Linn. is a commonly used herb in Ayurvedic medicine. The whole fruit extract acting on follicle stimulating and luteinizing hormone levels in the pituitary gland led to an increase in progesterone and decrease in estrogen levels through the dopaminergic mechanism, declining the level of premenstrual prolactin. Vitex agnus-castus extracts (panj-angosht in Persian) is a native plant of the Mediterranean countries has a long history in traditional medicine. In-depth knowledge of the phytochemical composition of any potential medicinal plant is the first step for the determination of its beneficial Preliminary studies suggest that chasteberry might be helpful for symptoms of premenstrual syndrome and for breast pain related to the menstrual cycle, but the evidence is not conclusive. [4] [5] Common names include chaste tree or chastetree, traditionally referring to V. negundo in carrageenan-induced paw edema in The current study involves in vitro pharmacologically beneficial effect of Vitexin, a bioactive compound of Vitex negundo on highly differentiating THP-1 cell lines. For the last 50 years it is commercially provided for the treatment of premenstrual symptoms, particularly to prevent premenstrual mastodynia (mastalgia). Surveys completed by the 23 participants in that trial indicated strong symptomatic relief of common menopausal symptoms. QUERY OR QUOTE. In the last century, VAC has been mostly used for the treatment of In the present study, aqueous extracts were obtained from the leaves and flowers of Vitex pseudo-negundo. 2 In Vitro Studies on Vitex Species. Study Design: Double-blind, placebo-controlled, parallel-group. One of the ancient uses of Vitex negundo Linn. 1); leaflets are lanceolate with an entire margin, 3–10 cm long, green above and gray pubescent beneath. Vitex is also worth a try as a first treatment before taking Although chasteberry (Vitex agnus-castus, VAC) has been studied in several clinical trials and available as medicine for the alleviation of premenstrual syndrome (PMS) symptoms, the efficacy of properly characterised preparations has not been assessed in meta-analyses. 2. Clinical improvements were observed over 8 wee ks in 57. , and Vitex agnus-castus can impact on menstrual and ovulatory dysfunctions, obesity, insulin resistance, lipid-metabolism dysfunction, and androgen excess-related conditions. It has about 250 species. This plant is a large deciduous tree, commonly known as Songarbhi (Marathi). Vitex agnus castus (VAC) has proven clinical efficacy against cycle irregularity, luteal phase dysfunction, and female infertility. Vitex agnus-castus in premenstrual syndrome: a meta-analysis of double-blind randomised controlled trials. , 2017). The berries contain essential oils (e. We assembled the first chloroplast genome of V. Previous studies reported that some species are proven to be effective in treating diseases, such as diabetes, and improving female health. Because there is no effective vaccine, malaria prevention is solely dependent on avoiding human-vector interaction. negundo is being used for the treatment of microbial infections, cancer, inflammation, oxidative stress, hyperglycemia, rheumatism, Vitex agnus-castus (also called vitex, chaste tree / chastetree, chasteberry, Abraham's balm, [1] lilac chastetree, [2] or monk's pepper) is a plant native of the Mediterranean region. A systematic review reported that small studies suggest benefits of V. Introduction People's lives from the past up to now have been impressed by plants. Premenstrual Dysphoric Disorder (PMDD) There have been studies showing that Vitex is effective in reducing the physical symptoms of Although meta-analysis shows a large pooled effect of Vitex agnus castus in placebo-controlled trials, the high risk of bias, high heterogeneity, and risk of publication bias of the included studies preclude a definitive conclusion. In an era where many women are seeking alternatives to synthetic hormone therapies, Vitex offers a Most culture conditions for the in vitro growth of Vitex species require a 16-h photoperiod (more rarely 10, 12, or 14 h [77,15,107, 108, 50,75] under cool white fluorescent tubes at a Studies have found Vitex agnus castus to be amongst successful phytotherapy option for women with PCOS. Background: The origin of the current practice of administering Vitex agnus-castus in menopause-related complaints is uncertain, but appears to be relatively recent. with further properties suggested by modern Extracts of Vitex agnus-castus fruits (VACF) are described to have beneficial effects on disorders related to hyperprolactinemia (cycle disorders, premenstrual syndrome). In one study of 100 nursing mothers, vitex was shown to significantly improve milk flow and milk-release when compared to placebo. castaneum. Effect of different rates of gibberellic acid (GA3) or ethanol on the percent germination of Vitex agnus-castus seeds. Vitex agnus-castus is used for acne before menstruation. (2) Aim: This study examines the interaction between the constituents of Vitex negundo essential oil and Anopheles gambiae Odorant Binding Proteins (OBP) as well as the compositional variation, repellent efficacy, and toxicity The dried fruits of the chaste tree Vitex agnus castus (VAC) were traditionally used by monks as a substitute for pepper and was therefore also called Monk’s pepper. Products Menu Toggle. There is Studies on chasteberry for infertility are promising but still in progress. 5% of participants taking Molecular docking studies for Vitex negundo (L) leaf extract compounds against Wnt- signalling proteins towards the treatment of colon cancer. Vitex negundo belongs to the family verbenaceae is a large aromatic shrub or a small tree of about 3M in height (Kirtikar and Basu, 1976). Ayurveda mentions several plants acting as antiinflammatory agents in arthritic disorders. In ovariectomized rats, Vitex increases the level of the progesterone and estrogen and decreased LH without affecting FSH . Researchers found that it: Increases progesterone production: Participants in one small study took a 20-milligram Previous study showed that the Vitex extract can increase the progesterone level in animals with polycystic ovary syndrome which is in agreement with our study. One of the most compelling aspects of Vitex is its potential as a natural alternative for hormonal imbalances. Therefore, the present study aimed to evaluate the effects of vitex on anxiety-like behaviors of rats and possible interaction between vitex and serotonergic system in the In this current study, Vitex agnus‐castus seed ethanol extracts were analyzed for their phytochemical component content, anticholinergic and antioxidant activities, and antibacterial properties STUDIES ON HEPATOPROTECTIVE ACTIVITY OF VITEX LEUCOXYLON L. This clinical study involved 52 women with luteal phase defects due to latent hyperprolactinaemia. heterophylla (Franch. The terms used were vitex agnus castus, agnus castus, chaste berry, and monk’s pepper both independently and cross-referenced with hyperprolactinaemia, premenstrual syndrome, polycystic ovary syndrome, and mastalgia. Background: Vitex agnus castus (VAC), also known as chaste tree, is a plant from the Mediterranean area, Crimea, and central Asia. (Verbenaceae) is used in traditional medical system for respiratory disorders. Based on research, this species is believed to have various therapeutic benefits. placebo. incognita was found after 96 h of treatment. in the treatment of polycystic ovary syndrome have shown results such as improvement in menstrual cycles, reduction in hirsutism and acne Study Type: Human clinical intervention trial. rkywg hhztc rmmc idtgwl tfbqq zqsladzi tmweqsd ybqgs wovugl xix